Uricol sachets Composition:
Each sache1 (5 g) contains:
Hexamine 500.00 mg
Piperazine citrate 190.00 mg
Khellin 1.83 mg
Uricol sachets Properties :
URICOl is a multifunctional formulation combining three active ingredients, each complementing the other with potent urinary antiseptic and antispasmodic. URICOL, is an antiseptic that prevents and treats urinary tract infections and asymptomatic bacteruria. In acidic urine, hexamine is hydrolyzed to formaldehyde which exerts potent antimicrobial effect against Gram-positive and Gram-negative bacteria and fungi. Hexamine is safe for long-term use and no emergence of resistance occurs. Piperazine citrate, the second ingredient in URICOL, adjusts the pH of urine to the appropriate value that helps dissolve uric acid and prevents formation and deposition of urate calculi. Khellin, the third ingredient in URICOL, is a powerful antispasmodic that relieves urinary smooth muscle spasm and hypermotility associated with infection, diagnostic procedures or irritations due to calculi. These properties demonstrate the superior antiseptic effects of URICOL and its high efficacy in relieving and overcoming urinary tract spasm, and reventing formation and deposition of unnary calculi. Formulation of URICOL in single dose (5 g) sachets, ensures pleasant taste and rapid absorption with fast onset of action.
Uricol sachets Indications:
– Chronic urinary tract infections, as in pyelitis, pyelonephritis, cystitis and infections accompanying neurogenic bladder.
– As a prophylaxis against urinary tract infection in patients with residual urine due to different causes including neuroloical ctseasss.os-proonqed bladder catheterization.
– fast relif of urinary tract spasms and irritations caused by crystalluria and urinary calculi
– Prevention of urinary tract lithiasis.
Uricol sachets Dosage and mode of administration:
The contents of one URICOL sachet is added to half a glass of water and taken during effervescence.
Chronic urinary tract infections, spasms of the urinary tract and prevention of urinary tract lithiasis: 1-2 sachets to be taken 3 – 4 times daily or as directed by the physician.
Uricol sachets Contraindications :
Hypersensitivity to any component of URICOL, severe hepatic diseases and renal insufficiency.
Uricol sachets precautions :
Hexamine containing prepartions should not be given to patients taking sulfonamides to avoid formation of insoluble precipitates in urinary tract
Uricol sachets Side effects :
URICOL is safe and well tolerated with almost no side effects However nausea, stomach upset of rash might rarely occur.
Uricol sachets pregnancy and lactation :
medications containing hexamine should be taken under medical .
supervision during pregnancy and lactation.
Uricol sachets Drug interactions:
Concomitant administration of hexamine with sulfonamides results in mutual antagomsm.
Interference with laboratory tests:
Overdosage and treatment :
None reported with effervescent formulations.
A box containing 6 or 12 sachets (5 9 each).
keep at temperature (15 – 3o C), away from moisture.
Keep oul of Ihe reach of children.
Uricol sachets produced by :