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Home Online Pharmacy

Sulbin vial

Drug Index by Drug Index
May 4, 2019
in Online Pharmacy
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Sulbin

Sulbin

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1 Sulbin Actions:
2 Sulbin INDICATIONS:
3 Sulbin CONTRAINDICATIONS:
4 Sulbin WARNINGS:
5 Sulbin Use in Pregnancy and Lactation:
6 Sulbin PRECAUTIONS :
7 PACKING:
8 STORAGE:
9 Produced by :

Sulbin Description:

Sulbactam sodium is a derivative 0f the basic penciillin nucleus. Chemically it is sodium penicillanate sulfone and is an off white crystalline powder highly soluble in water the molecular weight is 255.22 ampicillin sodium is derived from the penicillin nucleus 6 aminopenicillanic acid chemically it is D aminobenzyl penicillin sodium salt and has amolecular weight of 371.39
Sulbin im.iv.brand of sulbactam /ampicillin sodum combination is available as adry powder for reconstitution in vials containing the equivalent of 500 mg+1000mg , 250mg+500mg, 125mg+250mg of sulbactam and ampicillin respectively

Sulbin
Sulbin

 Sulbin Actions:

bichemical studies with cell free bacterial systems have shown sulbactam to be an irreversible inhibitor of most imprtant beta lactamases that occur in penicillin resistant organisms it possesses significant antibacterial activity only against neleseriaceae acinetobacter calcoaceticus bacteroides sp branhamella ,catarrhalls,and pseudomonas cepacla the potential for sulbactam sodum is preventing the destruction of penicillins and cephalosporins by resistant organisms was confirmed in whole organism studies using ressistant strains in which sulbactam sodum exhibited marked synergistic effects with penicillins and cephalosporins since sulbactam also binds to some penicillin binding proteins some sensitive strains are rendered mor susceptible to the combination than to the beta lactam antibiotic alone the bactericidal component of the combination is ampicillin which like benzyl penicillin acts against sensitive organisms during the stage of active multiplivation by the inhibition of biosynthesis of cell wall mucopeptide

 Sulbin INDICATIONS:

Sulbin im/iv is indicated for infections caused by susceptible microorganisms typical indications are upper and lower respiratory tract infections including sinusitis, otitis media and epiglottitis ,bacterial peneumonias, urinary tract infections and pyelonephritis intra abdominal infections including peritonitis, cholecystitis, endometritis, and pelvic cellulitis, bacterial peneumonias, urinary tract infections and pyelonephritis intra abdominal infections including peritonitis, cholecystitis, endometritis and pelvic cellulitis bacterial septicemia skin soft tissue bone and joint infections and gonococcal infections sulbin im/iv may also be administered peri operatively to reduce the incidence of post operative wound infections in patients undergoing abdominal or pelvic surgery in which peritoneal contamination may by persent in termination of pregnancy or cesarean section sulbin im/iv may be used prophylactically to reduce post operative sepsis

 Sulbin CONTRAINDICATIONS:

The use of this combination is contraindicated in Individuals with a history of an allergic reaction to any 0f the penicillins

 Sulbin WARNINGS:

who have experienced serever reactions whe

Serious and occasionally latal hypersensitivity (anaphylactic) reactions have been reported in patients on penicillin therapy. These reactions are more apt to occur in individuals with ahistory of penicillin hypersensitivity and/or hypersensitivity reactions to multiple allergens there have been reports of individuals with ahistory of penicillin hypersensitivity who have experienced serever reactions when treated with cephalosporins before therapy with apenicillin careful inquiry should be made concerning previous hypersensitivity reactions to penicillin ,cephalosporins and other allergens if an allergic reactions occurs the drug should be discontinued and the appropriate therapy instituted

 Sulbin Use in Pregnancy and Lactation:

animal reproduction studies have revealed no evidence of impaired fertility or harm to the fetus due to sulbactam and ampicillin however safety for use in pregnancy and lactation has not been established

 Sulbin PRECAUTIONS :

As with any antabiotic Preparation. constant observation for Signs of overgrowth 0f nonsusceptible organisms Includinng fungi is essential Should  superinfection occur, the drug should be discontinued and/or appropirate therapy instituted. As with any potent systems agent. it is advisable to check periodically for organ system dysfunction during extended therapy; this includes renal. hepatic, and hematopoietic systems This is periodically Important In neonates especially when premature and other infants

 

 PACKING:

– 0.375 Vials contain 0 125 gm Sutbactam sodium 0,250 gm ampicillin sodium
– 750 Vials contain 250 gm Subactam sodium  0.500 gm ampicillin sodium
– 1,500 vials :is contain 0,500gm Subactam sodium I,000 gm ampicillin sodium

 STORAGE:

Before reconstitution:

Keep at temperature not exceecing 30 C. in dry place
Keep out 0f the reach 0f children

Produced by :

PHARCO PHARMACEUTICALS

Tags: ampicillinAntibioticpharco pharmaceuticalssulbactam
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