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Thread: Pituicytes and Herring Bodies picture - Endocrine Histology Atlas

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    Default Pituicytes and Herring Bodies picture - Endocrine Histology Atlas


    Endocrine (or internally secreting) glands are also named ductless glands, since they lack excretory ducts. Instead, the secretory cells release their products, hormones, into the extracellular space. From the extracellular space, the hormones may enter the blood stream, by which they reach their target organs. Alternatively, the hormones may affect nearby cells (paracrine acting hormones).

    The major endocrine glands are the pituitary gland, the pineal body, the thyroid gland, the parathyroid gland, the pancreas, the adrenal glands, the ovaries and the testes. In some of these glands/organs the endocrine tissue constitutes only part of the parenchyma of the organ (Which ones?). Small groups or individual endocrine cells are also found in a variety of other organs, e.g. the GIT and the kidneys.

    Pituitary Gland

    The pituitary gland (or hypophysis) is attached to the inferior surface of the brain by an extension of the nervous tissue of the tuber cinereum /eminentia mediana of the hypothalamus, the infundibulum. The infundibulum and small amounts of non-neural secretory tissue surrounding it form the hypophyseal stalk. The pituitary gland is located in the sella turica, the hypophyseal fossa of the sphenoid bone. The pituitary gland is surrounded by a thin connective tissue capsule. The loose connective tissue between the capsule and the periosteum of the sphenoid bone contains a dense plexus of thin-walled veins, which surround the entire pituitary gland.
    Pituicytes Herring Bodies picture Endocrine attachment.php?s=f4d68bd3c31666e8f6056e3c426feebe&attachmentid=1321&d=1439064116

    Macroscopically, the pituitary gland can be divided into neurohypophysis, which includes all neuroectodemal hypophyseal derivatives, and adenohypophysis, which includes all ectodermal hypophyseal derivatives. Adenohypophyseal tissue extending dorsally along the anterior and lateral surfaces of the hypophyseal stalk is also called pars tuberalis of the hypophysis. The remainder of the adenohypophysis can be divided into a pars intermedia and a pars distalis.

    The neurohypophysis contains abundant capillaries, particularly in its ventral portion where most hormone release occurs. Many of these capillaries are fenestrated (contain holes), facilitating delivery of hormones into blood. In the following image, a small section of pars intermedia is visible in the lower left corner.

    An interesting histologic feature of the neurohypophysis is the presence of Herring bodies. When viewed with an electron microscope, these are dilated areas or bulges in the terminal portion of axons that contain clusters of neurosecretory granules. The granules contain oxytocin or antidiuretic hormone, along with their associated neurophysins. Herring bodies often are seen in association with capillaries. They are somewhat difficult to identify unambiguously by light microscopy; in the image to the right, the label might better say "probable Herring bodies".

    The neurosecretory end-globules or the so-calledHerring bodies have been investigated with silver carbonate andGomori techniques and the relationship between these end-globules and pituicytes has been discussed.

    Die neurosekretorischen Endkörper oder die sogenanntenHerring-Körper wurden mit der Silbercarbonat-Methode und derGomori-Technik untersucht. Die Zusammenhänge zwischen diesen Endkörpern und den Pituicyten wurden besprochen.

    Les corpuscules terminaux neurosécrétoires ou les soi-disant corps deHerring ont été examinés avec la méthode au carbonate d'argent et la technique deGomori. Les relations entre ces corpuscules terminaux et les pituicytes furent discutées.


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    The nature of the so-called Herring bodies - Springer
    Blue Histology - Endocrines

    Last edited by Medical Photos; 08-08-2015 at 08:02 PM.

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