Uterus, leiomyosarcoma, microscopic pictures atlas FEM032.jpg Here is the microscopic appearance of a leiomyosarcoma. It is much more cellular and the cells have much more pleomorphism and hyperchromatism than the benign leiomyoma. An irregular mitosis is seen in the center.

Uterus, leiomyosarcoma, microscopic pictures atlas FEM033.jpg As with sarcomas in general, leiomyosarcomas have spindle cells. Several mitoses are seen here, just in this one high power field.

Uterus, leiomyosarcoma, microscopic pictures atlas FEM034.jpg Sarcomas, including leiomyosarcomas, often have very large bizarre giant cells along with the spindle cells. A couple of mitotic figures appear at the left and lower left.