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Thread: Angioedema images - Pediatric Atlas

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    Default Angioedema images - Pediatric Atlas

    Who is affected
    Angioedema is a common condition, affecting about 10-20% of people during their life, although some types are more common than others.
    Hereditary angioedema is rare, only affecting between 1 in 10,000 and 1 in 50,000 people worldwide.

    Your doctor can diagnose angioedema by examining the affected skin and discussing symptoms.
    However, further tests, such as blood tests or allergy tests, may be required to determine the type of angioedema.
    Idiopathic angioedema is only diagnosed if no cause can be found.

    How is angioedema treated?
    Although most cases of angioedema get better without treatment after a few days, medication is often used.
    For cases of allergic and idiopathic angioedema, antihistamines and oral steroids (steroid tablets) can be used to relieve the swelling.
    Drug-induced angioedema can usually be treated by using an alternative medication to treat whatever underlying condition you have.
    Although the condition cannot be cured, regular drug treatment can prevent attacks in people with hereditary angioedema.

    Swollen skin
    The swelling is caused by a collection of fluid in the deep layers of the skin.
    It most often affects the hands, feet, eyes, lips, or genitals. In severe cases, the inside lining of the throat and bowel can be affected (see below).
    The swelling usually appears suddenly, and is more severe than normal hives (nettle rash). It commonly lasts one to three days. There may be a prickling sensation in the affected area before swelling is visible.
    The swelling is not itchy and the skin may look a normal colour; however, many people with allergic or idiopathic angioedema also develop urticaria (hives), which is red and itchy.

    When to seek medical advice
    Contact your GP if you have an episode of angioedema that does not affect your breathing and you have not previously been diagnosed with the condition. You will need to have tests to determine what type of angioedema you have.

    Allergic angioedema
    Normally, your immune system protects your body from illness and infection by attacking germs in your body.

    Idiopathic angioedema
    Cases of angioedema without an identifiable cause are known as idiopathic angioedema. It may be that a problem with the immune system sometimes causes it to "misfire".
    Angioedema images Pediatric Atlas attachment.php?s=d970ff6ac88b7c8a8bc6db10f5db49f7&attachmentid=1756&d=1441140909

    Drug-induced angioedema
    Some medications can cause angioedema. Angiotensin-converting enzyme (ACE) inhibitors, which are used to treat high blood pressure (hypertension), are usually responsible.
    It's estimated that around 1-5% of people taking ACE inhibitors will develop drug-induced angioedema. Black people being treated with ACE inhibitors are three to four times more likely to develop this side effect than white people.
    Around one in four cases of drug-induced angioedema occurs during the first month of taking an ACE inhibitor. The remaining cases develop many months or even years after treatment begins.
    While they are useful in lowering blood pressure, ACE inhibitors can sometimes disrupt the "chemical balance" and trigger an episode of severe swelling.

    Hereditary angioedema
    Hereditary angioedema is caused by a genetic mutation (a change in the DNA) in the C1 esterase inhibitor (C1-inh) gene. Genes are single units of genetic material that code for characteristics such as eye and hair colour.

    Allergic angioedema
    You're likely to be asked if you have recently been exposed to any allergy-causing substances, such as nuts or latex. You may also be asked whether you have a history of other allergic conditions, such as urticaria (hives) or asthma. People with an allergic condition often develop other allergic conditions.

    Drug-induced angioedema
    If you are taking a medication known to cause drug-induced angioedema, your GP will withdraw that medication and prescribe an alternative. You should not stop taking any prescribed medication without advice from a health professional.

    Hereditary angioedema
    Hereditary angioedema can be diagnosed using a blood test to check the level of proteins regulated by the C1-inh gene. A very low level would suggest hereditary angioedema.
    The diagnosis and management of hereditary angioedema is highly specialised and should be carried out in a specialist immunology clinic.

    Idiopathic angioedema
    Idiopathic angioedema is usually confirmed by a "diagnosis of exclusion". This means a diagnosis of idiopathic angioedema can only be made after all the above tests have been carried out and a cause has not been found.

    Angioedema - Diagnosis - NHS Choices

    Last edited by Medical Photos; 09-01-2015 at 08:55 PM.

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