Results 1 to 1 of 1

Thread: Pearls in Steroid Induced ocular HTN

  1. #1
    Moderator
    Join Date
    Oct 2017
    Location
    Riyadh, Saudi Arabia
    Posts
    140
    Biography
    (Consultant Ophthalmologist at MALAZ MEDICAL GROUP)
    Country

    Country


    Default Pearls in Steroid Induced ocular HTN

    Pearls in Steroid Induced ocular HTN



    ✍️ steroids change the TM ability to process aqueous due Glycoaminoglycan accumulation

    ✍️ Alteration of TM endothelium phagocytotic ability

    ✍️ Prevent release of enzymes that normally depolymerize GAGs

    ✍️ Topical or oral corticosteroids can cause IOP rise

    ✍️ Ointment or creams periorbital and inhaled steroids can cause IOP increase

    ✍️ May be seen in patients endogenously producing excess steroids (e.g., Cushing’s syndrome)

    ✍️ 2 -5 weeks onset (often longer) to develop

    ✍️ About 2/3 of population are steroid responders

    ✍️ only 10% of steroid responders have significant problems

    ✍️ Response is dependent upon
    • Frequency
    • Dose
    • Genetic predisposition : TIGR/Myocillin gene( AR inheritance pattern).
    Pearls Steroid Induced ocular attachment.php?attachmentid=3467&d=1513498257

    High risk patients

    ✍️ Myopes
    ✍️ Pts with POAG
    ✍️ Children ( most dramatic response)

    Treatment:

    ✍️ medication cessation
    ✍️ Aqueous suppressants( beta blockers, CAIs,..)
    ✍️ Prostaglandins
    ✍️ ALT or SLT (poor prognosis )
    ✍️ Trabeculectomy with or without antimetabolites











    Attached Images  
    Last edited by Reda Gomah El Garia; 12-17-2017 at 08:11 AM.

  2. Similar Threads

    1. Genetics of steroid biosynthesis and function free book
      By Medical Videos in forum Genetics Books
      Replies: 0
      Last Post: 03-11-2010, 02:32 PM
    2. Overcoming Steroid Insensitivity in Respiratory Disease free book
      By Medical Videos in forum Pulmonology Books
      Replies: 0
      Last Post: 12-09-2009, 11:49 PM
    3. Atlas of ophthalmology (eye atlas) Steroid Granuloma , Subconjunctival
      By Medical Videos in forum Ophthalmology Atlas(Photos of cases)
      Replies: 0
      Last Post: 03-16-2008, 05:04 PM
    4. Steroid-Free Astelin(R) Nasal Spray (R) Demonstrated Seasonal Allergy Symptom Improve
      By Medical Videos in forum E.N.T (Ear,Nose and Throat)
      Replies: 0
      Last Post: 03-30-2007, 12:26 PM

Tags for this Thread

Bookmarks

Bookmarks

Posting Permissions

  • You may not post new threads
  • You may not post replies
  • You may not post attachments
  • You may not edit your posts
  •  
About us
Medical Educational Site for Medical Students and Doctors Contains Free Medical Videos ,Atlases,Books,Drug Index ,Researches ,Health and Medical Technology news.
  • Privacy Policy
  • Join us
    Powered by vBulletin® Version 4.2.0 Copyright © 2015
  • vBulletin®
  • Solutions, Inc. All rights reserved. vBulletin Metro Theme by
  • PixelGoose Studio