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Thread: Plavix 75 mg tablets

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    Default Plavix 75 mg tablets

    Composition: CLOPIDOGREL (AS HYDROGEN SULPHATE) 75 MG

    Therapeutic indications
    Prevention of atherothrombotic events
    Clopidogrel is indicated in:
    • Adult patients suffering from myocardial infarction (from a few days until less than 35 days), ischaemic stroke (from 7 days until less than 6 months) or established peripheral arterial disease.
    • Adult patients suffering from acute coronary syndrome:

    - Non-ST segment elevation acute coronary syndrome (unstable angina or non-Q-wave myocardial infarction), including patients undergoing a stent placement following percutaneous coronary intervention, in combination with acetylsalicylic acid (ASA).
    - ST segment elevation acute myocardial infarction, in combination with ASA in medically treated patients eligible for thrombolytic therapy.
    Prevention of atherothrombotic and thromboembolic events in atrial fibrillation
    In adult patients with atrial fibrillation who have at least one risk factor for vascular events, are not suitable for treatment with Vitamin K antagonists (VKA) and who have a low bleeding risk, clopidogrel is indicated in combination with ASA for the prevention of atherothrombotic and thromboembolic events, including stroke.


    Plavix tablets attachment.php?attachmentid=426&stc=1&d=1436535041

    Warnings and precautions
    If any of the situations mentioned below apply to you, you should tell your doctor before taking Plavix:

    • if you have a risk of bleeding such as
      • a medical condition that puts you at risk of internal bleeding (such as a stomach ulcer).
      • a blood disorder that makes you prone to internal bleeding (bleeding inside any tissues, organs or joints of your body).
      • a recent serious injury.
      • a recent surgery (including dental).
      • a planned surgery (including dental) in the next seven days.

    • if you have had a clot in an artery of your brain (ischaemic stroke) which occurred within the last seven days.
    • if you have kidney or liver disease.
    • if you have had an allergy or reaction to any medicine used to treat your disease.

    While you are taking Plavix:

    • You should tell your doctor if a surgery (including dental) is planned.
    • You should also tell your doctor immediately if you develop a medical condition (also known as Thrombotic Thrombocytopenic Purpura or TTP) that includes fever and bruising under the skin that may appear as red pinpoint dots, with or without unexplained extreme tiredness, confusion, yellowing of the skin or eyes (jaundice) (see section 4 'Possible side effects').
    • If you cut or injure yourself, it may take longer than usual for bleeding to stop. This is linked to the way your medicine works as it prevents the ability of blood clots to form. For minor cuts and injuries e.g., cutting yourself, shaving, this is usually of no concern. However, if you are concerned by your bleeding, you should contact your doctor straightaway (see section 4 'Possible side effects').
    • Your doctor may order blood tests.

    Pregnancy and breast-feeding
    It is preferable not to take this product during pregnancy.
    If you are pregnant or suspect that you are pregnant, you should tell your doctor or your pharmacist before taking Plavix. If you become pregnant while taking Plavix, consult your doctor immediately as it is recommended not to take clopidogrel while you are pregnant.
    You should not breast-feed while taking this medicine.
    If you are breast-feeding or planning to breast-feed, talk to your doctor before taking this medicine.
    Ask your doctor or pharmacist for advice before taking any medicine.

    Possible side effects
    Like all medicines, this medicine can cause side effects, although not everybody gets them.

    Contact your doctor immediately if you experience:

    • fever, signs of infection or extreme tiredness. These may be due to rare decrease of some blood cells.
    • signs of liver problems such as yellowing of the skin and/or the eyes (jaundice), whether or not associated with bleeding which appears under the skin as red pinpoint dots and/or confusion (see section 2 'Warnings and precautions').
    • swelling in the mouth or skin disorders such as rashes and itching, blisters of the skin. These may be the signs of an allergic reaction.

    The most common side effect reported with Plavix is bleeding. Bleeding may occur as bleeding in the stomach or bowels, bruising, haematoma (unusual bleeding or bruising under the skin), nose bleed, blood in the urine. In a small number of cases, bleeding in the eye, inside the head, the lung or the joints has also been reported.

    If you experience prolonged bleeding when taking Plavix
    If you cut or injure yourself, it may take longer than usual for bleeding to stop. This is linked to the way your medicine works as it prevents the ability of blood clots to form. For minor cuts and injuries e.g., cutting yourself, shaving, this is usually of no concern. However, if you are concerned by your bleeding, you should contact your doctor straightaway (see section 2 'Warnings and precautions').


    Other side effects include:
    Common side effects (may affect up to 1 in 10 people):
    Diarrhoea, abdominal pain, indigestion or heartburn.
    Uncommon side effects (may affect up to 1 in 100 people):
    Headache, stomach ulcer, vomiting, nausea, constipation, excessive gas in stomach or intestines, rashes, itching, dizziness, sensation of tingling and numbness.
    Rare side effect (may affect up to 1 in 1000 people):
    Vertigo.
    Very rare side effects (may affect up to 1 in 10,000 people):
    Jaundice; severe abdominal pain with or without back pain; fever, breathing difficulties sometimes associated with cough; generalised allergic reactions (for example, overall sensation of heat with sudden general discomfort until fainting); swelling in the mouth; blisters of the skin; skin allergy; sore mouth (stomatitis); decrease in blood pressure; confusion; hallucinations; joint pain; muscular pain; changes in taste of food.
    In addition, your doctor may identify changes in your blood or urine test results.

    References:
    http://xpil.medicines.org.uk/ViewPil.aspx?DocID=11005
    https://www.medicines.org.uk/emc/med...+75mg+tablets/











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