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Thread: Innohep 20.000 u.i (10.000/0.5ml ) syring 0.5ml

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    Default Innohep 20.000 u.i (10.000/0.5ml ) syring 0.5ml

    Composition: TINZAPARIN SODIUM 20000 IU/ML


    Indications:
    Innohep belongs to a group of medicines called anticoagulants. It is a type of heparin called a low molecular weight heparin.
    Innohep changes the way your blood clots. This means your blood keeps flowing smoothly inside your blood vessels. These are the tubes that carry blood around your body and are called arteries and veins.
    Innohep is used to help stop:
    • Harmful blood clots forming in your veins following an operation. An example is a clot in a vein deep inside your body. This is usually in your leg (deep vein thrombosis or DVT for short).
    • Harmful blood clots forming in the tubing of an artificial kidney machine during kidney dialysis (haemodialysis).
    Innohep 20.000 (10.000/0.5ml syring 0.5ml attachment.php?attachmentid=317&stc=1&d=1435840108
    Do not have Innohep
    • If you are allergic (hypersensitive) to tinzaparin or any of the other ingredients in your medicine. You can find a list of these ingredients in section 6 of this leaflet.
    • If you know that you have, or have ever had, a big drop in the clotting cells (platelets) in your blood, caused by having any type of heparin (reaction called heparin-induced thrombocytopenia).
    • If you have any condition which makes you bleed severely, such as haemophilia.
    • If you have very high blood pressure.
    • If you have severe liver problems.
    • If you have a stomach ulcer.
    • If you know that you have a condition called endocarditis (an inflammation of the lining of the heart and heart valves).
    • If you have had a brain haemorrhage (bleeding inside your brain).
    • If you have an injury to your spine, head, eyes or ears.
    • If you have recently had, or are about to have an operation involving your spine, head, eyes or ears.
    • If you may be having a miscarriage.
    Important: If you are having an epidural or spinal anaesthetic
    You must remind your doctor that you are having Innohep before you receive any anaesthetic.
    If you are pregnant please also read the section of this leaflet "Pregnancy and breast-feeding".
    After you have the anaesthetic your doctor or nurse will make regular checks. This is to check if you are getting any major bleeding or bruising around your spine. This may cause paralysis that could be permanent.
    Any signs this may be happening to you include tingling, weakness or numbness in your lower legs or body, back pain or problems in going to the toilet. This happens very rarely.
    After you have the anaesthetic your doctor will tell you when you can take your medicine again.
    Take special care with Innohep
    Before you have Innohep tell your doctor:
    • If you have any condition which makes you more likely to bleed more easily. Ask your doctor if you are unsure.
    • If you are allergic (hypersensitive) to heparin.
    • If you are allergic to other low molecular weight heparins, such as enoxaparin or dalteparin.
    • If you have kidney problems. Your doctor may need to adjust your dose.
    • If you know you have a condition called diabetes mellitus.
    • If you know you have a condition called metabolic acidosis.
    • If you know you have any medical condition which may cause high levels of potassium in your blood (hyperkalaemia). Ask your doctor if you are unsure.
    • If you are taking a medicine from the group called potassium-sparing diuretics, such as amiloride or spironolactone. These are commonly called water tablets.
    • If you are taking another medicine that may affect your blood clotting.
    For a list of these medicines see the section "Taking other medicines".
    • If you have an artificial heart valve.
    Your doctor may take a blood test before you start having this medicine, and while you are having it. This is to check the level of the clotting cells (platelets) and potassium in your blood.
    This medicine may make you bleed more easily.
    The doctor or nurse should take care when giving you any other injections or procedures.
    This medicine must not be injected into your muscles.
    Taking other medicines
    Please tell your doctor or pharmacist if you are taking, or have recently taken any other medicines. This includes any medicines which you have bought without a prescription.
    You must tell your doctor or pharmacist if you are taking any of the following medicines:
    • Non-steroidal anti-inflammatory drugs, such as ibuprofen or diclofenac: for arthritis or aches or pains. You may be likely to bleed more easily.
    • Salicylates, such as aspirin: for reducing pain and inflammation, or for stopping harmful blood clots forming. You may be likely to bleed more easily.
    • Platelet aggregation inhibitors, such as clopidogrel: for stopping harmful blood clots forming. You may be likely to bleed more easily.
    • Thrombolytic agents, such as streptokinase: for dissolving blood clots. You may be likely to bleed more easily.
    • Vitamin K antagonists, such as warfarin: for stopping harmful blood clots. You may be likely to bleed more easily.
    • Activated protein C: for getting rid of blood clots. You may be likely to bleed more easily.
    • Dextrans: for increasing your blood volume. You may be likely to bleed more easily.

    Pregnancy and breast-feeding
    Please ask your doctor or pharmacist for advice before having Innohep:
    • If you are pregnant, or think you are pregnant.
    • If you are breast-feeding.
    Tell your doctor if you become pregnant while having this medicine.
    You must not have an epidural anaesthetic to help with your labour if you are having Innohep

    Side effects:
    Like all medicines, Tinzaparin sodium can cause side effects, although not everybody gets them.
    Important side effects to look out for
    You must get urgent medical help if you have any of the following symptoms. You may be getting an allergic reaction:
    • You have difficulty breathing
    • Your face or throat swell
    • Your skin develops a severe rash
    • Your skin develops blisters at the site of your injection
    • Your skin peels.
    You must get urgent medical help if you have any of the following symptoms after having an epidural or spinal anaesthetic. You may be developing paralysis:
    • Tingling, weakness or numbness in your legs or lower body
    • Back pain
    • Problems in going to the toilet.
    You should tell your doctor straight away if you spot any of the following signs which mean you may be starting to bleed severely:
    • Red or brown urine
    • Black tarry stools
    • Unusual bruising
    • Bleeding from your nose, or mouth or any operation wound that will not stop.
    Other possible side effects
    The side effects most often reported are blood problems and skin reactions, especially where your injection has been given.
    Very Common side effects (probably affect more than 1 in 10 people)
    • Bleeding (haemorrhage). This may be more likely if you are taking a high dose of Tinzaparin sodium.
    Common side effects (probably affect less than 1 in 10 people)
    • Bruising, pain or irritation at the site of the injection
    Uncommon side effects (probably affect less than 1 in 100 people)
    • Rash
    • Itchy skin
    • Hives
    • Headache
    • Blood tests results may show changes in the way your liver is working
    Side effects where the number of people affected is not known
    • Changes in your blood test results. This may lead to bruising or bleeding more easily, because of a reaction in your blood. Your blood may form more harmful clots. A drop in the number of clotting cells (platelets) in your blood may give you these symptoms. Your doctor can explain this more.
    • Changes in your blood test results. The amount of potassium may be increased. This is more likely to happen if you have severe kidney problems or diabetes. Your doctor can explain this more.
    • Problems with your heart if you have an artificial heart valve. This may be because you are not
    having the dose of Tinzaparin sodium that is right for you.
    • Your bones may weaken and break more easily. This is known as osteoporosis and has been seen in patients taking heparin for a long time.
    • Prolonged, painful erections in men.
    If any of the side effects become serious, or if you notice any side effects not listed in this leaflet, tell your doctor or pharmacist.











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