Pedical syrup Composition :
each 5 ml contains :
calcium gluconate 760 mg
vitamin D3 400 i u
vitamin B12 10 mcg
Pedical syrup Indications :
Dietary supplement contains calcium , vitamin D3 and vitamin B12
Pedical syrup Dosage :
Unless otherwise prescribed by the physician the usual dose is :
Children(2 to 12 years) : 1/2 – 1 teaspoonful daily
Adolescents : one teaspoonful daily
Pedical can also be taken by adding the dose to milk or water
Pedical syrup Precaution and warning :
Diarrhea may occur particularly in those receiving high doses . do not give to patients with increased blood galactose. the intake of calcium may influence the absorption and efficacy of some medicinces avoide overdose and prolonged use. contraindicated in hypercalcemia and hypercalciuria. for long time with high dose one should monitor calcium in urine and blood avoid over dosage.
Keep out of the reach of children
Pedical syrup Pack :
Carton box containing glass bottle of 100 ml with inner pamphlet
Pedical syrup Storage :
Store at temperature not exceeding 30 o c
Pedical syrup Produced by :
Egyphar obour city – egypt
Calcium Gluconate PPT power point presentation :
1. Calcium Gluconate
2. Contents • Introduction • Synonyms • Formula • Properties • Preparation • Pharmacological Properties • Therapeutic Applications • Side Effects • Drug Interactions • Contraindications
3. Introduction of Calcium Gluconate • Anhydrous Compound • Mineral Supplement • Essential Body Electrolyte • Muscle and Nerve Integrity • Also Essential for Muscle Contraction Cardiac Functions Coagulation of the Blood
4. Synonyms of Calcium Gluconate •Calcium D-gluconate •Calcium salt of Gluconic acid •Gluconic Acid hemi-calcium salt
5. Formula of Calcium Gluconate Chemical Formula = C12H22CaO14 Structural Formula =
6. Properties of Calcium Gluconate •Solubility = Slowly in H2O, Insoluble in organic solvent and alcohol. •Natue = Inorganic and Mildly acidic •Appearnce = Powder and granules. •Odour = Odorless
7. Preparation of Calcium Gluconate Oxidation of Glucose to Gluconic acid In the presence of calcium..
8. Pharmacological Properties of Calcium Glucoante •Plays role in physiology of organism and cell. •Pivotal role in signal transduction pathway. •Acts as 2nd messenger in neurotransmitter release of neurons and contraction of all muscle cell types. •Many enzymes require calcium ions as a cofactor. Notable example is blood clotting cascade.
9. Pharmacological Properties of Calcium Gluconate •Extracellular calcium is important for maintaining potential difference across excitable cell membranes as well as bone formation. •Calcium is absorbed from the small intestine by active transport and passive diffusion. •It crosses placenta and enters in breast milk.
10. Therapeutic Applications of Calcium Gluconate • Hypocalcemia: • Related to Hypothyroidism. • Magnesium Sulphate Overdose: • Hydrofluoric acid Burns: • Calcium gluconate reacts with hydrofluoric acid to form insoluble, nontoxic calcium fluoride.
11. Therapeutic Applications of Calcium Gluconate • Hyperkalemia: • Black Widow spider bites: • As an anti-dot • Muscle Cramping:
12. Side Effects of Calcium Gluconate • Nausea, Constipation, Stomach upset • Rapid I.V may cause hypercalcemia which can result in vasodilation, cardiac arrhythmias, decreased Blood Pressure and bradycardia. • I.M may lead to local necrosis and abscess formation.
13. Drug Interactions of Calcium Gluconate • Digoxin • Antacids or other calcium supplements. • Vitamin-D supplement. • Doxycycline. • Tetracycline.
14. Contraindications of Calcium Gluconate • Hypercalcemia • Ventricular Fibrillation. • Kidney Problem