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Home Online Pharmacy

Myolgin capsules

Drug IndexbyDrug Index
January 18, 2019
inOnline Pharmacy
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Myolgin capsules 

Myolgin capsules

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1 Myolgin capsules Pharmaceutical form :
2 Myolgin capsules Pharmacological Action :
3 Myolgin capsules Pharmakinetics :
4 Myolgin capsules Indications :
5 Myolgin capsules Dosage & Administration :
6 Myolgin capsules Contra-Indications :
7 Myolgin capsules side effects :
8 Myolgin capsules Drug Interactions :
9 Myolgin capsules Pregnancy & lactation :
10 Myolgin capsules Warnings and Prtcautions :
11 Myolgin capsules Package & Storage :
12 Myolgin capsules Manufactured by :

Myolgin capsules composition :

Each capsule contains 250 mg of Chlorzoxazone & 300 mg of Paracetamol

Myolgin capsules Pharmaceutical form :

Gelatin Capsule

Myolgin capsules Pharmacological Action :

Myolgin is Muscle relaxant and Analgesic.
Chlorzoxazone is a centrally acting skeletal muscle relaxant If acts primarily at the spinal cord level and subcortical areas of the brain when: it inhibits multisynpatic reflex areas involved in producing and maintainig skeletal musele spasm of varied etiology this results in reduced skeletal muscle spasm relief of pain and increased mobility of involved muscles Paracitamol has analgsic and antipyretic properties, It is as potent as aspirin in inhibiting prostaglandin synthesis in the CNS. The analgesic action of paracetamol adds to that which results SttOndariiy from
muscle relaxation.
Myolgin capsule offers quick relief of pain and restores mobility even in severe painful spasms of the skeletal muscles. Myolgin (aspirin free) is used safely with patients allergic to aspirin, in hemophilia and upper GI disease (e.g. ulcer, gastritis).

Myolgin capsules Pharmakinetics :

Chlorzoxazone is rapidly absorbed and can be detected in serum within 0.5 hour. It reaches its peak blood levels in about 1 to 2 hours. Its onset of action is 1 hour. Chlorzoxazone is rapidly metabolized and excreted in urine primarily as glucoronide conjugate. Its half – life is 60 mins, Paracetamol is rapidly and completely absorbed from the Gl tract with peak. plasma concentrations within 0.5 to 2 MOrs. It is uniformly distributed throughout most body fluids, It is extensively metabolized and excreted in urine primarily as inactive glucuronide and sulphate conjugates. The half-life in plasma is about 2 hours.

Myolgin capsules Indications :

Myolgin capsules s indicated for the relief of severe skeletal muscle spasm associated with acute painful musculoskeletal conditions as:
– low back pain
– Cervical root and disc syndromes
– Sprains and Strains
– Myalgia
– Torticollis
– Tension headaches
– Traumatic muscle injurtS and fibrosis

Myolgin capsules Dosage & Administration :

The usual adult dosage is one capsule to be taken 3 or 4 times daily.
N.B. take with food or water if GI upset occurs.

Myolgin capsules Contra-Indications :

Myolgin capsule is contraindicated with known hypersensitivity to any components of the preparation Avoid in patients with liver disease.

Myolgin capsules side effects :

Occasional Gl disturbances, dizziness, nausea, lightheadedness or drowsiness, malaise or overstimulation may be noted. Rarely, a patient may note discoloration of the urine resulting from a phenolic metabofite of Chlorzoxazone.

Myolgin capsules Drug Interactions :

Alcohol and other CNS depressants: They cause drowsiness that may be additive to that induced by chlorzoxazone. They also may increase the potential of hepatotoxicity of paracetamol.

Myolgin capsules Pregnancy & lactation :

Safety of Chlorzoxazone during p”‘gnancy or lactation has not been established. Use only when clearly needed and when the potential benefits outweigh the potential hazards,

Myolgin capsules 
Myolgin capsules

Myolgin capsules Warnings and Prtcautions :

Serious (including Fatal) hepatocellular toxicity has been reported rarely in patients receiving chlorzoxazone. The mechanism is unknown but appears to be idiosyncratic and unpredictable. Factors predisposing patients to this rare event are not known. Patients should be instructed to report early signs and/or symptoms of hepatotoxicity such as fever, rash, anorexia, nausea, vomiting, fatigue, right upper quadrant pain, dark urine, or jaundice. Chlorzoxazone should be discontinued immediately and a physician consulted if any of these signs or symptoms develops. Chlorzoxazone use should also be discontinued if a patient develops abnormal liver enzymes (e.g. AST, AlT, Alkaline phosphatase and bilirubin). The concomitant use of alcohol or other central nervous system depressents have an additive effect If a sensitivity reaction occurs such as urticaria, redness or itching of the skin, the medicine should be stopped.
If any signs or symptoms suggestive of liver dysfunction are observed, the medicine should be discontinued. Dosage in excess of the recommended ones may cause severe liver damage. Patients suffering from kidney disease should take this medicine under medical supervision.

Myolgin capsules Package & Storage :

– Myolgin Capsule is provided in strips of 10 Capsules in a pack of 2 strips.
– Store below 30′ C.

– KEEP All MEDICAMENTS OUT OF THE REACH OF CHILDREN

Myolgin capsules Manufactured by :

GlaxoSmithKline SAE.
El Salam City, Cairo, A.R.E.

Tags: ChlorzoxazoneGlaxoSmithKlineParacetamol
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