Kenacomb cream composition:
Each gm. contains:
Nystatin (Squibb Mycostatin) 100,000 units
Neomycin base (as Neomycin sulphate) 2.5 mg.
Gramicidin 0.25 mg.
Triamcinolone Acetonide 1.0 mg.
Base: perfumed vanishing cream for the Kenacomb Cream and plastibase for the Ointment (Squibb polyethylene- mineral oil gel base ).
Kenacomb cream action:
Triamcinolone Acetonide is a potent topical steroid with marked anti inflammatory, antipruritic and antiallergic effects. It provides rapid, complete and often prolonged control of the symptoms and signf. cutaneoue
Nystatin provides specific anticandidal activity, specially against candida albicans. Neomycin and Gramicidin provide combined action against a wide range of Gram- positive and Gram-negative bacteria. With this combination bacterial resistance has not been a problem.
Kenacomb cream indications:
– Atopic eczema
– Nummular eczema
– Contact eczema
– Post traumatic infective eczema
– Follicular eczema
– Seborrheic eczema
– Infantile eczerna
– Stasis eczema
– Otitis externa
– Anogenital pruritis
Because of the high incidence of pathogeniC bacteria or fungi which can complicate the response to plain cortico steroids used on apparently non-infected skin conditions, treatment with Kenacomb is rational and effective.
Kenacomb cream dosage and administration:
Apply a thin film to the affected area 2-3 times daily.
Kenacomb cream contra-indications:
Skin tuoerculosis, most viral lesions (herpes Simplex, vaccinia and varicella) and fungal lesions not susceptible to Nystatin.
Kenacomb cream precautions:
Occlusive dressing should be avoided. In infants, long-term continuous topical steroid should, be avoided for fear of adrenal suppression. In animals, topical steroid adminis- tration may cause abnormalities in foetal development. The relevance of this finding to human beings has not been established, however, prolonged use in great amounts should not be practiced during pregnancy. The unproven theoretical teratogenic hazard must be placed in pers- pective against the need for corticosteroids 1.0 maintain the health of patients.
Kenacomb cream side effects:
It is well tolerated, systemic toxicity has not been a problem, Sensitivity to Neomycin and/or Gramicidin may occur.
Ointment : Tubes of 5, 10 and 15 gm.
Cream : Tubes of 5, 10 and 15 gm.
produced by :
Bristol- Myers Squibb Egypt.