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Home Online Pharmacy

Gynipral tablets and ampules

Drug Index by Drug Index
September 30, 2019
in Online Pharmacy
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GYNIPRAL

GYNIPRAL

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1 Gynipral tablets and ampules composition :
2 Gynipral tablets and ampules properties:
3 Gynipral tablets and ampules indications:
4 Gynipral tablets and ampules administration:
5 Gynipral tablets and ampules contra-indications:
6 Gynipral tablets and ampules side effects:
7 Notice:
8 Gynipral tablets and ampules Precautions:
9 Package:
10 Manufactured by:

Gynipral tablets and ampules composition :

Each ampoule 2 ml contains:
Hexoprenaline Sulphate     10 mcg
Each Tablet contains:
Hexoprenaline Sulphate     0,5 mg

Gynipral tablets and ampules properties:

– It is a selective b2 sympathomimetic agent which relaxes the uterus, by decreasing or arresting both the frequency and the intensity of the uterine contractions ,
– It inhibits both the spontaneous and induced labour,
– It stabilizes strong or irregular uterine contractions of the uterus during delivery
– It has Slighter effects on the heart rate and circulation than many other sympathomimetic drugs,
– Gynipral in the majority of cases, prevents the possibility of premature labour and prolongs gestation until the normally expected date of birth,

GYNIPRAL
GYNIPRAL

Gynipral tablets and ampules indications:

During Pregnancy:
Gynipral prevents threatened abortion with premature labour following the 23 rd gestational week, It also avoids labour during cervical suture operations and other surgical interventioas in the gravid uterus following the 12 th gestational week,
During Delivery:
Gynipral is indicated in acute intrauterine asphyxia ( fetal distress ), irregular labour and hypermotility of the uterus, diagnosis of compression of the cord and preparation of caesarean section. It is indicated prior to version of transverse presentations, in prolapse of cord and dystocic labour,

Gynipral tablets and ampules administration:

Ampules:
For I. V, Administration only:
– Dilute 2 ml Gynipral ampoule (10 mcg) with 8 ml saline solution to produce 10 ml to be injected I.V slowly), during 5-10 minutes to suppress uterine centraction spontaneously,
Tablets:
Imminent miscarriage or premature delivery: After a precedent administration of Gloipral ampoules, treatment with Gynipral 0.5 mg tablets is started about I – 2 hour prior to the discontinuation of the administration of the Gynipral infusions, Initially one tablet is taken every 3 hours, Later on more widely spaced intervals every 4 – 6 hours (8 to 4 tablets a day).

Gynipral tablets and ampules contra-indications:

Massive genilal bleeding, abruptio placentae, tachycardiac arrhythmia, intrauterine infections, it should be administered with caution in thyrotexicosis, myocarditis, hypoteasion, severe renal failure, mitral valve defects and idiopathic hypertrophic suhvalvular aortic stenosis,

Gynipral tablets and ampules side effects:

During the I. V, use of Gynipral, tachycardia may occur but is generally well tolerated by the patient Increase of the heart rate to levels above 120/minute is a sign of overdosage and can rapidly be normalized by reduction of the dose, The fetal heart rate is seldomly affected. There may be an occasional drop in the maternal hlood pressure lasting for a few minutes, Sometimes dose- related individaal and dizziness, nausea may occur.

Notice:

Gynipral should not be combined with other sympathomimetic drugs, theophylline preparations, MAO – inhibiters, and halogenated aaaestheties (because they might intensify side effects on circulation) ,

Gynipral tablets and ampules Precautions:

It is advisable to regularly check maternal blood pressure during administration of Gynipral It is also advisable to monitor the fetal heart rate every 15 minutes initially and every six hours later on. In case of intrauterine asphyxia, continuous monitoring of these parameters is imperative. In long term administration of the infusion it is advisable to reduce the intake of Iluid and salt , Patients sbould be examined for signs of oedema,
Patients should be kept in the left lateral position as a prophylactic measure against the vena cava compression syndrome  Overdosage of it can be conlrolled by adminisrranon of a B Blocker,

 Package:

Ampoules 10 ug n ml in packs of 5 & 25 Ampoule,
Tablets: box one or 100 tablet in strips,

Manufactured by:

the arab drug company cairo A.R.E

Tags: GYNIPRALThe Arab Drug Company
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