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04-18-2015, 10:05 PM


Treating high blood pressure during surgery, controlling congestive heart failure associated with heart attack, treating chest pain in certain patients, and lowering blood pressure during surgery.

Nitroglycerin is a nitrate. It works by relaxing (widening) blood vessels. Chest pain occurs when the heart needs more oxygen than it can get. Relaxing blood vessels allows blood to flow more easily. This reduces the heart's workload and the amount of oxygen needed by the heart.



you are allergic to any ingredient in nitroglycerin
you have had a stroke or other bleeding in the brain, swelling of the sac surrounding the heart, or interference of blood returning to the heart
you are taking avanafil, riocituat, sildenafil, tadalafil, or vardenafil
Contact your doctor or health care provider right away if any of these apply to you.

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Before using nitroglycerin:

Some medical conditions may interact with nitroglycerin. Tell your doctor or pharmacist if you have any medical conditions, especially if any of the following apply to you:

if you are pregnant, planning to become pregnant, or are breast-feeding
if you are taking any prescription or nonprescription medicine, herbal preparation, or dietary supplement
if you have allergies to medicines, foods, or other substances
if you drink alcoholic beverages
if you have a history of other heart problems (eg, heart failure, enlarged heart, heart attack), overactive thyroid, stroke or other bleeding in the brain, or recent head injury
if you have anemia, low blood pressure, dehydration, or low blood volume
Some MEDICINES MAY INTERACT with nitroglycerin. Tell your health care provider if you are taking any other medicines, especially any of the following:

Avanafil, beta-blockers (eg, propranolol), calcium channel blockers (eg, diltiazem), diuretics (eg, furosemide, hydrochlorothiazide), medicines for high blood pressure, phenothiazines (eg, thioridazine), riociguat, sildenafil, tadalafil, or vardenafil because the risk of low blood pressure and dizziness on standing may be increased
Salicylates (eg, aspirin) because they may increase the risk of nitroglycerin's side effects
Long-acting nitrates (eg, nitroglycerin patch) because they may decrease nitroglycerin's effectiveness
Alteplase because it may decrease nitroglycerin's effectiveness
Heparin because its effectiveness may be decreased by nitroglycerin
This may not be a complete list of all interactions that may occur. Ask your health care provider if nitroglycerin may interact with other medicines that you take. Check with your health care provider before you start, stop, or change the dose of any medicine.

Side effects of nitroglycerin:

All medicines may cause side effects, but many people have no, or minor, side effects. Check with your doctor if any of these most COMMON side effects persist or become bothersome:

Dizziness or light-headedness; headache; irritation at the injection site.

Seek medical attention right away if any of these SEVERE side effects occur:
Severe allergic reactions (rash; hives; itching; difficulty breathing; tightness in the chest; swelling of the mouth, face, lips, or tongue); blurred vision; dry mouth; fainting; fast or irregular heartbeat; flushing; heavy sweating; pale skin; restlessness; severe or persistent dizziness or headache; severe or persistent nausea or vomiting; unusual tiredness or weakness.

This is not a complete list of all side effects that may occur. If you have questions about side effects, contact your health care provider.