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04-13-2015, 08:57 PM


* Isoptin SR (240 mg Verapamil hydrochloride) 20 Sustained - release Film-Coated Tablets.
Calcium antagonist, cardioselective for the treatment of hypertension.
* Composition: Each sustained-release film-coated tablet contains:
Verapamil hydrochloride 240 mg in a Sustained-release formulation.
* Indications:
- Hypertension.
- Secondary prevention after acute myocardial infarction.
* Dosage and mode of administration:
- The dose of Isoptin SR 240 mg, individualized according to the severity of the disease are to be taken regularly
as prescribed by the physician.
- The film coated tablets are to be swallowed whole with some liquid, preferably with or shortly after meals.
- Unless otherwise instructed, the daily dose is 1 film coated tablet in the morning (patients requiring particularly
gradual blood pressure lowering should be started on half a tablet taken in the morning).
- If after about 2 weeks of treatment a dose increase is found to be necessary, the dose can be raised to
a maximum of 2 film coated tablets daily.
- On long-term treatment, a daily dose of 480 mg should not be exceeded.
- Short-term dose increases are possible only when directed by the physician.
- In patients with impaired hepatic function, the effect of Verapamil is intensified and prolonged depending
on the severity of the liver disease due to diminished drug metabolism. In these cases, dosage should be
adjusted with special care starting with the lowest possible dose.
* Contraindications:
- Cardiovascular shock.
- Complicated acute myocardial infarction (bradycardia, marked hypotension, left ventricular failure).
- Severe conduction disorders (2nd and 3rd degree AV block).
- Sick sinus syndrome (bradycardia, tachycardia syndrome).
* Warnings in the leaflet must be revised.
* Store at a temperature not exceeding 30 degrees C, protect from light.
* Manufactured by: Kahira Pharmaceuticals & Chemical Industries Company.
Under Licence of: Abbott Laboratories - USA & its subsidiary in Germany.
* Barcode: 6221068907009 (same as that for: ISOPTIN SR RETARD 240 MG 30 TAB).

Whether this medicine is suitable for you
Verapamil hydrochloride is not suitable for everyone and some people should never use it. Other people should only use it with special care. It is important that the person prescribing this medicine knows your full medical history.

Your prescriber may only prescribe this medicine with special care or may not prescribe it at all if you:

are allergic or sensitive to or have had a reaction to any of the ingredients in the medicine
have certain types of muscular dystrophy
have kidney problems
have Lambert-Eaton syndrome
have liver problems
have low blood pressure
have myasthenia gravis
have or have had certain heart problems
have Wolff-Parkinson-White syndrome
Furthermore the prescriber may only prescribe this medicine with special care or may not prescribe it at all for a child.

As part of the process of assessing suitability to take this medicine a prescriber may also arrange tests:

to check that this medicine is having the desired effect
Over time it is possible that Verapamil hydrochloride can become unsuitable for some people, or they may become unsuitable for it. If at any time it appears that Verapamil hydrochloride has become unsuitable, it is important that the prescriber is contacted immediately.