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03-06-2015, 08:41 AM
DEPONIT NT 10 - 37.4 or 5 - 18.7 MG 7 PATCHES



Nitroglycerin is used for:

Treating high blood pressure during surgery, controlling congestive heart failure associated with heart attack, treating chest pain in certain patients, and lowering blood pressure during surgery.

Nitroglycerin is a nitrate. It works by relaxing (widening) blood vessels. Chest pain occurs when the heart needs more oxygen than it can get. Relaxing blood vessels allows blood to flow more easily. This reduces the heart's workload and the amount of oxygen needed by the heart.

Do NOT use nitroglycerin if:

you are allergic to any ingredient in nitroglycerin
you have had a stroke or other bleeding in the brain, swelling of the sac surrounding the heart, or interference of blood returning to the heart
you are taking avanafil, riocituat, sildenafil, tadalafil, or vardenafil
Contact your doctor or health care provider right away if any of these apply to you.

Before using nitroglycerin:

Some medical conditions may interact with nitroglycerin. Tell your doctor or pharmacist if you have any medical conditions, especially if any of the following apply to you:

if you are pregnant, planning to become pregnant, or are breast-feeding
if you are taking any prescription or nonprescription medicine, herbal preparation, or dietary supplement
if you have allergies to medicines, foods, or other substances
if you drink alcoholic beverages
if you have a history of other heart problems (eg, heart failure, enlarged heart, heart attack), overactive thyroid, stroke or other bleeding in the brain, or recent head injury
if you have anemia, low blood pressure, dehydration, or low blood volume
Some MEDICINES MAY INTERACT with nitroglycerin. Tell your health care provider if you are taking any other medicines, especially any of the following:

Avanafil, beta-blockers (eg, propranolol), calcium channel blockers (eg, diltiazem), diuretics (eg, furosemide, hydrochlorothiazide), medicines for high blood pressure, phenothiazines (eg, thioridazine), riociguat, sildenafil, tadalafil, or vardenafil because the risk of low blood pressure and dizziness on standing may be increased
Salicylates (eg, aspirin) because they may increase the risk of nitroglycerin's side effects
Long-acting nitrates (eg, nitroglycerin patch) because they may decrease nitroglycerin's effectiveness
Alteplase because it may decrease nitroglycerin's effectiveness
Heparin because its effectiveness may be decreased by nitroglycerin
This may not be a complete list of all interactions that may occur. Ask your health care provider if nitroglycerin may interact with other medicines that you take. Check with your health care provider before you start, stop, or change the dose of any medicine.

How to use nitroglycerin:

Use nitroglycerin as directed by your doctor. Check the label on the medicine for exact dosing instructions.

Nitroglycerin is given as an injection at your doctor's office, hospital, or clinic. Contact your health care provider if you have any questions.
If you miss a dose of nitroglycerin, contact your doctor right away.
Ask your health care provider any questions you may have about how to use nitroglycerin.

Important safety information:

Nitroglycerin may cause dizziness, light-headedness, or blurred vision. These effects may be worse if you take it with alcohol or certain medicines. Use nitroglycerin with caution. Do not drive or perform other possibly unsafe tasks until you know how you react to it.
Do not drink alcohol while you are using nitroglycerin. Alcohol toxicity has occurred in patients on high-dose intravenous injection. Certain medicines (eg, disulfiram, cephalosporins, furazolidone, metronidazole, monoamine oxidase inhibitors [MAOIs]) may increase the risk of alcohol toxicity if you drink alcohol while using nitroglycerin.
Check with your doctor before you drink alcohol while you are using nitroglycerin. Drinking alcohol may increase the risk of low blood pressure with nitroglycerin.
Nitroglycerin may cause dizziness, light-headedness, or fainting; alcohol, hot weather, exercise, or fever may increase these effects. To prevent them, sit up or stand slowly, especially in the morning. Sit or lie down at the first sign of any of these effects.
Contact your doctor right away if you develop slow heartbeat or new or worsening chest pain after you take nitroglycerin.
Tell your doctor or dentist that you take nitroglycerin before you receive any medical or dental care, emergency care, or surgery.
Nitroglycerin contains propylene glycol, which may interfere with some triglyceride tests.
You may need to check your blood pressure often while using nitroglycerin. Talk with your doctor.
Use nitroglycerin with caution in the ELDERLY; they may be more sensitive to its effects.
PREGNANCY and BREAST-FEEDING: If you become pregnant, contact your doctor. You will need to discuss the benefits and risks of using nitroglycerin while you are pregnant. It is not known if nitroglycerin is found in breast milk. If you are or will be breast-feeding while you are using nitroglycerin, check with your doctor. Discuss any possible risks to your baby.
When used for long periods of time without a break, nitroglycerin may not work as well. This is known as TOLERANCE. Increasing the dose is not effective in managing tolerance to nitroglycerin. Tolerance to other nitrates or nitrites may also occur. Be sure to have a "nitrate-free" period of time each day to help prevent this tolerance. Talk with your doctor if nitroglycerin stops working well. Do not take more than prescribed.

Some people who use nitroglycerin for a long time without a break may develop a physical need to continue taking it. This is known as physical DEPENDENCE. If you use nitroglycerin without a break and then suddenly stop using it, you may get WITHDRAWAL symptoms. These may include chest pain, heart attack, or possibly sudden death. Be sure to have a "nitrate-free" period of time each day; this may help prevent dependence and withdrawal problems.

Possible side effects of nitroglycerin:

All medicines may cause side effects, but many people have no, or minor, side effects. Check with your doctor if any of these most COMMON side effects persist or become bothersome:

Dizziness or light-headedness; headache; irritation at the injection site.

Seek medical attention right away if any of these SEVERE side effects occur:
Severe allergic reactions (rash; hives; itching; difficulty breathing; tightness in the chest; swelling of the mouth, face, lips, or tongue); blurred vision; dry mouth; fainting; fast or irregular heartbeat; flushing; heavy sweating; pale skin; restlessness; severe or persistent dizziness or headache; severe or persistent nausea or vomiting; unusual tiredness or weakness.

This is not a complete list of all side effects that may occur. If you have questions about side effects, contact your health care provider. Call your doctor for medical advice about side effects. To report side effects to the appropriate agency, please read the Guide to Reporting Problems to FDA.