Medical Videos
06-05-2009, 09:36 AM
Membranoproliferative (mesangiocapillary)
Causes:
Idiopathic © Hepatitis C © B ©infective endocarditis
Investig:
1 Serum C3 ¯ (hypocomplementemia) MCQ
1 Biopsy :
Light membrane thickened.
Åcell ¯ (esp. mesangio.)
E/M details type I subendoth. Deposits.
Type II dense deposits intra
Membranous.
immunoflurescence C3 - Ig G.
& In type II there is a nephritic factor (Ig G activate c).
& Prognosis both types bad prognosis, type II recurs in
transplanted kid.
C/P: Some cases presented with
nephritic or nephrotic haematuria
-mixed picture are common as :
hypertension - haematuria + heavy proteinuria
nephritic nephrotic
ttt : steroids - cytotoxic drugs ( no definite value) – antiplatlet
G.N. with ¯ C.
Membranoproliferative - poststreptococcal - SLE
Source: Internal Medicine Book of Dr.Osama Mahmoud (Ain Shams University)
Causes:
Idiopathic © Hepatitis C © B ©infective endocarditis
Investig:
1 Serum C3 ¯ (hypocomplementemia) MCQ
1 Biopsy :
Light membrane thickened.
Åcell ¯ (esp. mesangio.)
E/M details type I subendoth. Deposits.
Type II dense deposits intra
Membranous.
immunoflurescence C3 - Ig G.
& In type II there is a nephritic factor (Ig G activate c).
& Prognosis both types bad prognosis, type II recurs in
transplanted kid.
C/P: Some cases presented with
nephritic or nephrotic haematuria
-mixed picture are common as :
hypertension - haematuria + heavy proteinuria
nephritic nephrotic
ttt : steroids - cytotoxic drugs ( no definite value) – antiplatlet
G.N. with ¯ C.
Membranoproliferative - poststreptococcal - SLE
Source: Internal Medicine Book of Dr.Osama Mahmoud (Ain Shams University)