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01-20-2016, 07:22 PM
METHYLDOPA 250 MG
2801
PACKAGE LEAFLET: INFORMATION FOR THE USER
MEDOMET 250 mg &
500 mg TABLETS
METHYLDOPA
1. What Medomet is for
2. Before you take Medomet
3. How to take Medomet
4. Possible side effects
5. How to store Medomet
6. Further information
The name of your medicine is Medomet. It contains the
active ingredient Methyldopa, which belongs to a group of
medicines called anti-hypertensives. It is used to lower
high blood pressure, (hypertension).
If you are not sure why you have been prescribed this
medicine then please ask your doctor.
Do not take Medomet and tell your doctor if you:
• are allergic (hypersensitive) to Methyldopa or any of the
other ingredients in these tablets (listed in section 6 of
this leaflet)
The signs of an allergic reaction include a rash, itching or
difficulty breathing.
• have active liver disease (such as hepatitis or cirrhosis)
• are suffering from depression
• have high blood pressure due to a tumour on the adrenal
gland, near the kidney (phaeochromocytoma)
• have an inherited blood disorder of the red blood
pigment haemoglobin known as acute porphyria
• are taking MAOIs (monoamine oxidase inhibitors) for
depression
Do not take this medicine if any of the above apply to you.
If you are not sure, talk to your doctor or pharmacist before
taking Methyldopa.
Take special care with Medomet
Tell your doctor before you take this medicine if you:
• have kidney disease.
• have previously had liver disease.
• have a history of depression.
• suffer from an abnormal breakdown of red blood cells
which can make the skin pale or yellow and cause
weakness or breathlessness (haemolytic anaemia).
If you are not sure if any of the above apply to you, talk to
your doctor or pharmacist before taking Medomet.
Operations and tests
If you are going to have an operation or an anaesthetic, tell
your doctor, dentist or nurse that you are taking Medomet.
Medomet may affect the results of certain laboratory tests.
Regular checks, (before the start of treatment and for 6-12
weeks after), may be carried out on blood cells and liver
function.
Taking other medicines
Tell your doctor or pharmacist if you are taking or have
recently taken any other medicines, including medicines
bought without a prescription. This is because Medomet
can affect the way some medicines work. Also some
medicines can affect the way Medomet works.
In particular, tell your doctor or pharmacist if you are taking
any of the following medicines:
• other medicines to treat high blood pressure such as
captopril, enalapril (ACE inhibitors), doxazosin, prazosin
(alpha-blockers), candesartan, losartan (angiotensin-II
receptor antagonists), clonidine, diazoxide, guanethidine,
hydralazine, minoxidil, moxonidine or sodium
nitroprusside
• medicines to treat high blood pressure or chest pain
(angina) such as propranolol, atenolol (beta-blockers),
amlodipine, felodipine (calcium-channel blockers),
bendroflumethiazide, furosemide (diuretics), glyceryl
trinitrate, isosorbide mononitrate (nitrates)
• medicines to treat anxiety or mental health problems
such as diazepam, lorazepam, temazepam,
chlorpromazine, haloperidol, pimozide or lithium
• medicines known as MAOIs, (monoamine oxidase
inhibitors), used to treat depression such as phenelzine,
moclobemide or tranylcypromine
• medicines known as NSAIDs, (non-steroidal
anti-inflammatory drugs), for pain and inflammation such
as aspirin, ibuprofen or indometacin
• steroids such as hydrocortisone or prednisolone to treat
swelling and allergies
• medicines to treat Parkinson’s disease such as levodopa
or entacapone
• muscle relaxants such as baclofen and tizanidine
• oestrogens used for contraception or hormone
replacement therapy (HRT)
• moxisylyte to treat blood circulation problems like
Raynaud’s disease
• salbutamol used to treat asthma and other airways
problems
• alprostadil for problems maintaining an erection
• aldeslukin to treat cancer
• iron supplements
AVOID ALCOHOL whilst taking Medomet tablets. This is
because alcohol can affect the way Medomet works.
Pregnancy and breast-feeding
If you are pregnant, planning to become pregnant, or are
breast-feeding, ask your doctor or pharmacist for advice
before taking Medomet or any other medicine.
Driving and using machines
Medomet tablets may make you feel drowsy. Make sure
you are not affected before you attempt to drive or operate
machinery.
Taking this medicine
Always take Medomet tablets exactly as your doctor has
told you. You should check with your doctor or pharmacist
if you are not sure.
These tablets should only be taken by mouth. Swallow
them whole with water.
Adults
The usual starting dose is 250 mg, two times a day, for 2
days. After which your doctor may gradually increase the
dose at intervals of 2 or more days, until an adequate
response is achieved. The maximum dose is 3 g daily.
Children
The usual starting dose is 10 mg per kg of bodyweight
daily taken in 2 - 4 divided doses, increased as required up
to a maximum of 65 mg per kg of bodyweight or 3 g daily,
whichever is less.
Elderly
The usual starting dose is 250 mg a day (e.g. 125 mg twice
daily). Your doctor may gradually increase the dose if
necessary, up to a maximum of 2 g a day.
Medomet may be given with, or instead of, other medicines
to lower blood pressure and the doses may need to be
amended.
If you take more Medomet than you should
If you (or someone else) take too many tablets, contact
your doctor or the nearest hospital casualty department
immediately. Take this leaflet and the container with you so
they know what has been taken.
Read all of this leaflet carefully before you
start taking this medicine.
- Keep this leaflet. You may need to read it again.
- If you have any further questions, ask your doctor
or pharmacist.
- This medicine has been prescribed for you.
Do not pass it on to others. It may harm them,
even if their symptoms are the same as yours.
- If any of the side effects become serious, or if you
notice any side effects not listed in this leaflet,

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References
METHYLDOPA 250MG TABLETS | Drugs.com (http://www.drugs.com/uk/methyldopa-250mg-tablets-leaflet.html)