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12-05-2011, 12:43 PM
Optocetine 0.5 %
Eye Drops
Each 10 ml contains :
Chloramphenicol 0.05 gm
Optocetine 0.5 % eye drops contains chloramphenicol which is a broad spectrum antibacterial agent against many gram negative and gram positive organisms such as Staphylococcus aurous , Streptococci including Streptococcus pneumonia and Streptococcus haemolyticus , E.coli , Heamophilus influenza ,Staphylococcus pneumonia , Klebsiella enterobacter spp., Moraxella lacunata , Morax-Axenfeld bacillus and Neisseria spp.

Indications & usage :
Optocetine 0.5 % eye drops is used for treatment of superficial ocular
infections due to strains of microorganisms susceptible to chloramphenicol
including :-
Conjunctivitis .
Keratitis .
Blepharitis .
Endophthalmitis .
Corneal ulcer .

Hypersensitivity to chloramphenicol.
Side effects:
Sensitivity reactions such as transient stinging, itching and urticaria may occur in some patients.
Warnings & precautions:
chloramphenicol should be used only in serious infections or when other drugs are ineffective or contraindicated.
As with other antibacterial agents prolonged use may lead to overgrowth of non-susceptible organisms, if this occur, drug is to be stopped and appropriate measures should be taken.
Hematopoietic sensitivity may rarely occur and is usually reversible on cessation of the drug.
Rare cases of a plastic anemia have been reported with prolonged or frequent
intermittent use of chloramphenicol .
Dosage & administration :
Apply 1 or 2 drops every 4-6 hours daily for the first 3 days depending upon the severity of condition. Intervals between applications can be increased after the first two days . N.B.
Therapy should be continued for 48 hours after healing.

A carton box containing self dropper plastic bottle of 10 ml solution . Storage:
Stored in refrigerator at (2-8) oc and bottle should not be used for more than 4
weeks after first opening .

12-11-2011, 12:01 PM
Has anyone heard about the use of cloramphenicol over the counter -antibiotic eye drops - commonly used to treat conjunctivitis as a first line therapy for infected ingrowing nails in healthy patients? I had been informed by another podiatrist that it was acceptable for use but havent been able to find any details anywhere.