Anti-glaucoma drugs in pregnant and lactating women is always debatable issue…
On request from my dear colleague
✅ summarized in the following points about anti-glaucoma drugs in pregnant and lactating woman
✍️ if newly discovered with low risk or glaucoma suspect we can postpone ttt until the 2nd trimester( specially if we know that IOP usually decrease during pregnancy naturally)
✍️ if high risk we can start with beta blockers, alpha agonist, topical CAIs ( the lowest dose and frequency) but stop beta blockers and alpha agonist at 8th month to avoid side effects on the fetus during labor
✍️ ALT and SLT is also an option
✍️ PG absolutely contraindicated during pregnancy as it may precipitate premature uterine contractions and abortion.
✍️ systemic CAI contraindicated in pregnancy and lactating woman ( teratogenic and metabolic acidosis with renal failure)
Anti-glaucoma drugs in pregnant and lactating women power point presentations:
Anti-glaucoma Drugs (Ocular Pharmacology)
Anti-glaucoma Drugs (Ocular Pharmacology)
Presentation Layout
Introduction to glaucoma
Anti glaucoma drugs:
– Classification
– Indications
– Contraindications
Summary
Mode of action of anti glaucoma drugs
Beta blocker-decrease aqueous secretion
Miotics -increase trabecular outflow
Adrenergic agonist-decrease aqueous secretion
Prostaglandin-increase trabecular and uveaoscleral outflow
Carbonic anhydrase inhibitor-decrease aqueous secretion
For Further Reading
Clinical Ocular Pharmacology by Jimmy D Balett
Ophthalmic Drugs by Graham Hopkins & Richard Pearson
Comprehensive Ophthalmology by A.K. Khurana
AAO-Section 10-Glaucoma
AAO-Section 2-Fundamentals & Principles of Ophthalmology
Internet
Medical Treatment of Glaucoma Fritz Allen ,MD Visionary Ophthalmology
Pharmacotherapy of . Glaucoma Dr Manjuprasad Moderator: Dr Vijayalaxmi M.K
Glaucoma – ancient greek meaning clouded or blue- green hue • In Hippocratic aphorisms Glaucoma – blindness coming from advancing years • Second leading cause of blindness. Glaucoma is not a single disease process but a group of disorders characterized by a progressive optic neuropathy resulting in a characteristic appearance of optic disc & specific pattern of irreversible visual field defects that are associated frequently but not invariably with ↑IOP. Classification • Congenital glaucoma – Primary congenital glaucoma – Developmental glaucoma • Primary adult glaucoma – Primary open angle glaucoma – Primary angle closure glaucoma – Primary mixed mechanism glaucoma • Secondary glaucoma. Pathogenesis • All types of glaucoma – progressive optic neuropathy due to the death of retinal ganglion cells(RGCs) • RGCs death is initiated – block in transport of neurotrophins from brain to RGCs damaging cascade activation Apoptosis of RGCs • RGCs death – loss of retinal fibers – optic neuropathy & visual field defects.