Allerfen tablets composition :
Each fablet contains:
fexofenadine HEI 60 mg or 180 mg .
Allerfen tablets properties :
Fexofenadine is the active metabolite of terfenadine.
It is referred to as non-sedating antihistamine with selective peripheral H 1 receptor antagonist effect, Fexofenadine has a rapid long lasting activity with no anticholinergic effect at the recommended dosage.
Allerfen tablets pharmacokinetics :
-Fexofenadine hydrochloride is rapidly absorbed into the body following oral administration with T max occurring 1-3 hours post dose
-Fexofenadine undergoes negligible hepatic and non-hepatic metabolism
-The major route of elimination is believed to be through biliary excretion, while 10% of the ingested dose is excreted unchanged through the urine
Allerfen tablets Indications :
It is indicated for the relief of symptoms associated with:
« Allergic rhinitis and sinusitis
« Allergic skin conditions as pruritus and urticaria
« Allergic conjunctivitis
Allerfen tablets dosage and administration :
• Adults and children> 12 years of age:
– Allergic rhinitis and conjunctivitis 120 mg daily as single or 2 divided doses.
– Allergic skin conditions 180 mg/day .
• Children 6-12 years of age: 30 mg twice daily
Allerfen tablets contraindications :
Patients who are hypersensitive to the active ingredients
Allerfen tablets precautions :
A dose of one tablet (60 mg) once daily is recommended as the starting dose in patients with decreased renal function.
Allerfen tablets adverse reactions :
-Very minimal adverse reactions has been observed during the use of Fexofenadine ,and was similar to placebo.
-The commonly observed adverse reactions are Drowsiness 1.3% fatigue 1.3% and headache 1%
Allerfen tablets during pregnancy and lactation :
There are no adequate and well controlled studies in pregnant and lactating women.
How Supplied :
• Tablets 60 mg: Strips of 10 tablets in packs of 1 strip or 2 strips.
• Tablets 180 mg: Strips of 5 tablets in packs of 2 strips.
Keep all medicaments out of reach -of children
AMOUN PHARMACEUTICAL Co. SA£.
EI-Obour City, Cairo, Egypt.