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Home Online Pharmacy

Abimol Tablets

Drug IndexbyDrug Index
February 1, 2019
inOnline Pharmacy
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Abimol Tablets

Abimol Tablets

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1 Abimol Tablets Pharmacological Action :
2 Abimol Tablets Pharmacokinetics in Renal Impairment :
3 Abimol Tablets Indication :
4 Abimol Tablets Dosage & Administration :
5 Abimol Tablets Contra-Indications :
6 Abimol Tablets Side Efftects :
7 Abimol Tablets Precaution & Warnings :
8 Abimol Tablets Package & Storage :
9 Abimol Tablets Instruction to Patient :
10 Abimol Tablets Manufactured by :

Abimol Tablets Composition :

– Tablet containing 500 mg of Paracetamol
– Syrup each Srnl contains 150mg of Paracetamol
– Each Suppository contains 300 mg of Paracetamol

Abimol Tablets Pharmaceutical Form :

Tablet, Syrup & Suppository

Abimol Tablets Pharmacological Action :

Mild analgesic and anttpvretic. and is recommended for the treatment of most painful and febrile conditions.

Abimol Tablets Pharmacokinetics :

Paracetamol is rapidly and almost completely absorbed from the gastrointestinal tract. The concentration in plasma reaches a peak in 30 to 90 minutes and the plasma half-life IS 1 – 4 hours after therapeutic doses, Paracetamol is relativtely uniformly distributed throughout most body fluids. Binding of the drug to plasma proteins is variable; 20 to 30% may be bound at the concentrations encountered during acute intoxication. Following therapeutic doses 90 – 100% of the drug may be recovered in the urine within the first day. However, practicaflv no paracetamol is excreted unchanged and the bulk is excreted after hepatic conjugation.

Abimol Tablets
Abimol Tablets

Abimol Tablets Pharmacokinetics in Renal Impairment :

An increase in the interval between doses of paracetamol has been recommended for adults with chronic renal failure.Haemodialysis may result in reduced plasma levels of paracetamol and therefore supplementary doses of paracetamol maybe necessary in order to maintain therapeutic blood levels.

Abimol Tablets Pharmacokinetics in Hepatic Impairment :

In mild liver disease, there is no evidence that paracetamol is harmful when taken at recommended doses. However, in severe fiver disease. the plasma paracetamol half-life is significantly prolonged

Abimol Tablets Indication :

Analgesic and antipyretic. and is recommended for the treatment of most painful and febrile conditions, for example headache including migraine and tension headaches. toothache , backache. rheumatic and muscle pains. dysmenorrhoea, sore throat. and for relieving the fever, aches and pains of colds and flu. Also recommended for the symptomatic relief of pain due to non-serious arthritis.

Abimol Tablets Dosage & Administration :

Adults:
One to two tablets every 4 to 6 hours up to four times daily as required. Maximum daily dose is 4000 mg. Do not exceed the
stated dose. Do not take more than 8 tablets in 24 hours. Do not take more frequently than every four hours
Children: Children should not be given Abimol for more than 3 days without consulting a doctor. No more than 4 doses tobe taken in any 24 hour period. The maximum daily dose is 60 mg/Kg
6 – 12 years: Half to one tablet three or four times daily as required.
1 – 6 years: 5 to 10 ml of the liquid suspension (120 to 240 mg of paracetamol). Dose may be repeated after 4 hours.
3 months to less than 1 year: 2.5 to 5 ml of the liquid suspension (GO to 120 mg of paracetamol). Dose may be repeated after 4 hours.
less than 3 months: 2.5ml of the liquid suspension may be administered to infants who develop pyrexia after vaccination at 2 months of age. If necessary. a second dose can be given 4-6 hours later. If pvrexia persists after the second dose, medical attention is required.
For all other indications in this age group, use only under medical supervision.
Abimol should not be used with other paracetamol containing products.

Abimol Tablets Contra-Indications :

Abimol is contraindicated in patients with a previous history of hypersensitivity to paracetamol or excipients.

Abimol Tablets Side Efftects :

– Paracetamolhas been widely used and, when taken at the usual recommended dosage. side effects are mild and infrequent and reports of adverse reactions are rare.
– Skin rash and other allergic reactions, such as anqioedema occur rarely.
– In patients sensitive to aspirin or other NSAIDs. aggravation of bronchospasm has been reported.
– Most reports of adverse reactions to paracetamol relate to overdose with the drug.
– Isolated cases of blood dyscrasia. thrombocytopenic purpura. haemolytic anaemia and agranulocytosis have been recorded.
– chronic hepatic necrosis has been reported in a patient who took daily therapeutic doses of paracetamol for about a year and liver damage has been reported after daily ingestion of excessive amounts for shorter periods. Differences in the abnormalities of tlver function in those who were long-term users of paracetamol nor was the control of their disease improved after paracetamol withdrawal.
– Nephrotoxic effects following therapeutic doses of peracetemol are uncommon.

Abimol Tablets Drug Interaction :

The anticoagulant effect of warfarin and other coumarins may be enhanced by prolonged regular daily use of paracetamol with increased risk of bleeding; occasional doses have no significant effect.

Abimol Tablets Preqnancy & Lactation :

Human and animal studies have not identified any risk to pregnancy, Human studies have not identified any risk to lactation or the breast-fed offspring. Paracetamol crosses the placental barrier and is excreted in breast milk

Abimol Tablets Precaution & Warnings :

Care is advised in the administration of paracetamol to patients with severe renal or severe hepatic impairment. The hazard of overdose is greater in those with non-cirrhotic alcoholic liver disease. Patients who are taking other potentially hepatotoxic drugs are at Increased risk of paracetamol-induced hepatotoxicity.

Abimol Tablets Package & Storage :

Tablets: Strips of 10 tablets in packs of 2 strips. Store below 30 C
Syrup: Bottle of 125ml
Suppository: Box of 5 suppositories

Abimol Tablets Instruction to Patient :

– Do not exceed the stated dose
– D0 not to take other paracetamol-containing products concurrently.
– If symptoms persist consult your doctor.
– If you have been diagnosed with liver or kidney impairment seek medical

advice before taking this medication

– KEEP ALL MEDICAMENTS OUT OF THE REACH OF CHILDREN

Abimol Tablets Manufactured by :

GlaxoSmithKline SAE.- El Salam city-Cairo- Egypt
For Suppositories: Manufactured by Smith Kline Beecham – Elharam-Giza for

GlaxoSmithKline SAE. -Egypt

Tags: GlaxoSmithKlineParacetamol
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