Human papilloma virus
Aetiology:
A. Causative organism: human papilloma virus (types 16 & 18 are oncogenic strains)
B. Mode of infection: like HSV.
C. Predisposing factors: multiple sexual partners.
Diagnosis:
– Condyloma acuminata: multiple cauliflower genital masses.
– Giant condyloma.
– Complications:
– Cervical & vulval cancer.
– In pregnancy:
– Rapid growth occurs but regress rapidly after delivery.
– Infection of the fetus during delivery leads to
laryngeal papiloma.

Investigations:
– Cytology: koilocytosis.
– Colposcopy: reveal subclinical types.
Treatment:
– Chemical cautery: by podophyllin 5 % (avoided during pregnancy).
– Delivery by CS.
– Treatment of CIN.
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