Herpes simplex virus

♦ The commonest genital ulcer.
Aetiology:
A. Causative organism: herpes simplex virus mainly type 2.
B. Mode of infection:
– Sexual route: sexual contact.
– Non-sexual route: materno-fetal.
C. Predisposing factors: multiple sexual partners.

Diagnosis:
– Sites of infection: vulva, vagina, cervix & perianal.
– Forms of infection:
– Primary: severe manifestations + fever.
– Secondary (recurrent): milder manifestations.
– Lesions: multiple painful vesicles which ulcerate
leaving painful shallow ulcer that heals
within 2 weeks.
– Complications:
– 1ry infection in the 1st half of pregnancy:
leads to abortion.
– Infection in the 2nd half of pregnancy: leads to preterm labour & infection of fetus.
– Neonatal death.
Investigations:
– Culture on human amnion cells.
– ELISA.
Treatment:
– Acyclovir: antiviral.
– Delivery: CS is indicated if :
– Visible lesions on the vulva.
– Before rupture of membranes or within 4 hours of ruptured membranes.

Herpes simplex virus

This video lecture explains the life cycle of herpes simplex virus and the infection strategy of HSV in causing herpes disease.

Herpes Virus NBDE & USMLE – HSV1 – HSV2 – VZV – EBV – CMV – HHV8

Introduction to Human Herpesviruses (HHV)

There are 8 human herpesviruses, and they are all double-stranded DNA viruses. They can cause both lytic or latent infection.
HHV can be divided into three subfamilies: alpha viruses (HSV-1, HSV-2, and VZV), beta viruses (CMV, HHV-6, HHV-7), and gamma viruses (EBV, HHV-8), each with their own characteristics.

Herpes (oral & genital) – causes, symptoms, diagnosis, treatment, pathology

What is herpes? Herpes is a virus causing sores most commonly around the mouth (oral herpes) and genitals (genital herpes).

What is Herpes? | Can Herpes be Cured?

Dr. Rowley as he talks over some of the most commonly asked questions about the herpes virus.
00:17 – What is herpes? 00:31 – What’s the difference? 01:10 – What are the symptoms of genital herpes? 01:57 – Do you always know if you have genital herpes? 02:36 – Can herpes be cured? 03:34 – How common is herpes? 04:43 – How is herpes tested for? 05:09 – Is herpes treatable? 06:17 – Can you still have sex if you have herpes? 07:21 – How common are herpes outbreaks? 08:21 – Which type of herpes is the worst? 08:59 – How can you get checked?

Herpes Simplex Virus

Herpes Simplex Virus • HSV type 1 (HSV-1) • HSV type 2 (HSV-2) • Common infections involve: – skin, eye, oral cavity, and genital tract. • In healthy: mild and self-limiting • immunocompromised and newborn: the infection may be severe and life threatening.

Herpes Simplex Virus

INTRODUCTION  EPIDEMIOLOGY AND TRANSMISSION  STRUCTURE  REPLICATION  PATHOGENESIS AND CLINICAL SIGNIFICANCE  LABORATORY DIAGNOSIS  TREATMENT AND PREVENTION