This is a video that demonstrates the technique of concurrent continuous renal replacement therapy and therapeutic plasma exchange (CCRRT+TPE). CCRRT+TPE may be useful in the treatment of children with fulminant hepatic failure, hemolytic uremic syndrome or patients with immune-mediated acute renal failure. The video was filmed by Kim Yaeger,BSN in the Center for Advanced Pediatric Education (CAPE) at Stanford University. The video was presented by Dr Peter Yorgin at the 2006 CRRT Conference in San Diego.